FPIN's Clinical Inquiries. Methylphenidate for management of fatigue in the palliative care setting.

Pharmacological treatments for fatigue associated with palliative care: executive summary of a Cochrane Collaboration systematic review

BACKGROUND In palliative care patients, fatigue can be severely debilitating and is often not counteracted with rest, thereby impacting daily activity and quality of life. Further complicating issues are the multidimensionality, subjective nature and lack of a consensus definition of fatigue. The review aimed to evaluate the efficacy of pharmacological treatments for fatigue in palliative care,...

Pharmacologic treatments for fatigue associated with palliative care.

BACKGROUND This review updates the original review, 'Pharmacological treatments for fatigue associated with palliative care' and also incorporates the review 'Drug therapy for the management of cancer-related fatigue'.In healthy individuals, fatigue is a protective response to physical or mental stress, often relieved by rest. By contrast, in palliative care patients' fatigue can be severely de...

Using aggregated single patient (N-of-1) trials to determine the effectiveness of psychostimulants to reduce fatigue in advanced cancer patients: a rationale and protocol

BACKGROUND It is estimated that 29% of deaths in Australia are caused by malignant disease each year and can be expected to increase with population ageing. In advanced cancer, the prevalence of fatigue is high at 70-90%, and can be related to the disease and/or the treatment. The negative impact of fatigue on function (physical, mental, social and spiritual) and quality of life is substantial ...

FPIN's clinical inquiries. Angiotensin blockade in patients with diabetic nephropathy.

FPIN's clinical inquiries. Monitoring therapy for patients with Alzheimer's disease.